The Indiana Pacers and Cleveland Cavaliers will meet in Game 1 of their Eastern Conference semifinal matchup on Sunday. Indiana is coming off a five-game first-round series win over the Milwaukee Bucks, while Cleveland swept the four-game series with the Miami Heat. The Pacers (50-32), second in the Central Division, averaged 117.4 points per game during the regular season. The Cavaliers (64-18), champions of the Central, won their first division title since the 2017-2018 season.
Tip-off from Rocket Arena in Cleveland is set for 6 p.m. ET. The Cavaliers are 8-point favorites in the latest Pacers vs. Cavaliers odds from DraftKings Sportsbook, while the over/under for total points scored is 229.5. The Cavaliers are -325 on the money line (risk $325 to win $100), while the Pacers are +260 (risk $100 to win $260). Before making any Cavaliers vs. Pacers picks, check out the NBA predictions from the SportsLine Projection Model.
The SportsLine Projection Model simulates every NBA game 10,000 times and has returned well over $10,000 in betting profit for $100 players on its top-rated NBA picks over the past six-plus seasons. The model enters the second full week of the 2025 NBA playoffs on a sizzling 156-116 roll on all top-rated NBA picks dating back to last season, returning nearly $4,000. It is also 22-11 (67%) on top-rated NBA against-the-spread picks this season. Anyone following at sportsbooks and on betting apps could have seen huge returns.
Now, the model has simulated Pacers vs. Cavaliers 10,000 times and just revealed its coveted NBA picks and betting predictions. You can head to SportsLine now to see the model’s picks. Here are several NBA odds and NBA betting lines for Cavaliers vs. Pacers:
- Pacers vs. Cavaliers spread: Cleveland -8 at DraftKings
- Pacers vs. Cavaliers over/under: 229.5 points
- Pacers vs. Cavaliers money line: Indiana +260, Cleveland -325
- IND: The Pacers have hit the money line in 44 of their last 62 games (+36.30 units)
- CLE: The Cavaliers have hit the game total over in 56 of their last 88 games (+20.80 units)
- Pacers vs. Cavaliers picks: See picks at SportsLine
- Pacers vs. Cavaliers streaming: FuboTV (Try for free)
Why the Cavaliers can cover
Center Jarrett Allen is one of seven Cleveland players averaging double-digit scoring in the 2025 NBA playoffs. In four playoff starts, he is averaging 14.3 points, 10.3 rebounds, 2.5 steals and 1.3 assists in 28 minutes. In the 124-87 win over Miami in Game 3, he recorded 22 points and 10 rebounds in just 26 minutes of action.
Shooting guard Donovan Mitchell has also been a force on offense. In four postseason starts, he is averaging 23.8 points, four assists, 3.3 rebounds and 1.5 steals. He scored 20 or more points in three games in the series against Miami, including back-to-back 30-point efforts in Games 1 and 2. In a 123-116 win over Boston on Feb. 28, he poured in 41 points, while adding five assists and three rebounds. See which team to back at SportsLine.
Why the Pacers can cover
Power forward Pascal Siakam has been a force this season. In three regular-season games against the Cavaliers, he averaged 17 points, eight rebounds, 2.7 assists and one block in 32.7 minutes. In 78 games in 2024-2025, all starts, he averaged 20.2 points, 6.9 rebounds and 3.4 assists. He has also had a lot of success against Cleveland throughout his career. In 28 matchups against the Cavaliers, he is averaging 17.8 points, 6.1 rebounds and 3.1 assists in 30 minutes.
Veteran center Myles Turner has also had success against the Cavaliers. In four games against Cleveland this year, he averaged 13.5 points, 5.8 rebounds and 1.3 blocks in 25.5 minutes. In 72 regular-season games in 2024-2025, he averaged 15.6 points, 6.5 rebounds, two blocks and 1.5 assists in 30.2 minutes. He is coming off a near double-double in the Game 5 series-clinching 119-118 overtime win over the Milwaukee Bucks on Tuesday. In that game, he poured in 21 points, while grabbing nine rebounds. See which team to back at SportsLine.
How to make Cavaliers vs. Pacers picks
SportsLine’s model has simulated Pacers vs. Cavaliers 10,000 times and is leaning Under the total, projecting 227 combined points. The model also says one side of the spread hits in nearly 60% of simulations. You can head to SportsLine to see the model’s NBA picks.
So who wins Pacers vs. Cavaliers, and which side of the spread hits in nearly 60% of simulations? Visit SportsLine now to see which side of the Pacers vs. Cavaliers spread to back, all from the model that has returned well over $10,000 on top-rated NBA picks, and find out.
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