The 2025 NCAA Tournament has reached the Final Four. For the second time in the history of March Madness, all four No. 1 seeds advanced to the Final Four and now we’ll see Auburn, Houston, Duke and Florida battle for the title on Saturday. Auburn vs. Florida (-2.5, 159.5) begins at 6:09 p.m. ET on Saturday, while Duke (-5.5, 136.5) vs. Houston will follow at 8:49 p.m. ET. Both games will be played at the Alamodome in San Antonio on CBS. Duke is the -115 favorite to win it all, followed by Florida at +310.
One major storyline that emerged from the Elite Eight was an arm injury to Auburn forward Johni Broome. He was able to return to practice on Thursday and told reporters he plans to be 100% by Saturday. How will the Broome injury impact the 2025 March Madness Final Four in San Antonio, and which Auburn vs. Florida score prediction and Duke vs. Houston score prediction should you make? Before locking in any 2025 NCAA Final Four predictions, be sure to check out the 2025 March Madness score predictions from SportsLine’s team of college basketball experts.
Thomas Casale, Jason La Canfora, Larry Hartstein, Bruce Marshall and Chip Patterson have all been making college basketball picks for SportsLine throughout the season and they all enter the Final Four on impressive streaks. Casale is 61-37 entering the final weekend of the college basketball season while La Canfora is 74-51-1, Hartstein is 61-45, Marshall is 99-72-1 and Patterson is on a 7-2-1 hot streak.
Be sure to see what this team of proven experts has to say before locking in your 2025 Final Four score predictions. You can only see their exact score predictions for both 2025 NCAA Tournament Final Four matchups at SportsLine.
Top 2025 NCAA Tournament Final Four score predictions
One Final Four score prediction: La Canfora is predicting that Florida takes down top overall seed Auburn, 83-78, in the first national semifinal. To what extent Broome’s injury limits his production looms large here, as he was dominating Michigan State before his exit and looked like he was clearly protecting himself after his return. However, even when Broome was healthy, Florida handled the Tigers pretty comfortably in a regular-season matchup at Auburn in February and the Gators have piled up high-profile wins all season.
“The Gators dropped 90 on Auburn at Auburn, which is hard for me to forget, and probably hard for the Tigers to forget. We are splitting hairs here but I feel like Florida is a little better and a little more balanced and their shot-makers will help them be a shot or two better here. Also like the fact that Alex Condon will be another week removed from some of his ankle issues,” La Canfora told SportsLine. See La Canfora’s prediction for Duke vs. Houston and the Final Four score predictions from all SportsLine’s other college basketball experts here.
How to make 2025 March Madness score predictions
One of SportsLine’s top college basketball experts is all-in on a team that’s a “covering machine.” You can only see which team it is at SportsLine.
Who should you back in the 2025 NCAA Tournament’s Final Four? Which “covering machine” will turn heads in San Antonio? Visit SportsLine now to see which teams you can back with confidence, all from a team of experts who have been locked in on college basketball all season.
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