The St. Louis Cardinals will look to turn around their recent fortunes when they battle the Pittsburgh Pirates in a key National League Central matchup on Monday. St. Louis is coming off an 18-7 loss at Boston and a three-game weekend sweep, while Pittsburgh defeated the New York Yankees 5-4 on Sunday. The Cardinals (4-5), who tied for second in the division at 83-79 last year, are 0-3 on the road this season. The Pirates (3-7), who finished fifth in the Central at 76-86 in 2024, are 1-2 on their home field.
First pitch from PNC Park in Pittsburgh is set for 6:40 p.m. ET. The Cardinals won eight of 13 meetings a year ago. St. Louis is a -125 favorite on the money line (risk $125 to win $100) in the latest Pirates vs. Cardinals odds from SportsLine consensus, while the total number of runs Vegas thinks will be scored, or the over/under, is 8. Before making any Cardinals vs. Pirates picks, be sure to see the MLB predictions and betting advice from SportsLine’s proven computer model.
The SportsLine Projection Model simulates every MLB game 10,000 times. It enters Week 3 of the 2025 MLB season on a 34-19 roll on top-rated run-line betting picks (+629). Anybody following at sportsbooks and on betting apps could have seen strong returns.
Now, the model has set its sights on Cardinals vs. Pirates and just locked in its picks and MLB predictions. You can head to SportsLine now to see the model’s picks. Now, here are several MLB odds and betting lines for Cardinals vs. Pirates:
- Cardinals vs. Pirates money line: St. Louis -125, Pittsburgh +105 at BetMGM
- Cardinals vs. Pirates over-under: 8.5 runs
- Cardinals vs. Pirates run line: St. Louis -1.5 (+134)
- STL: The Cardinals have covered the run line in 26 of their last 41 games (+9.15 units)
- PIT: The Pirates have hit the game total over in 16 of their last 25 home games (+7.05 units)
- Cardinals vs. Pirates picks: See picks at SportsLine
- Cardinals vs. Pirates streaming: FuboTV (Try for free)
Why the Cardinals can cover
St. Louis is expected to send left-hander Matthew Liberatore (0-0, 4.50 ERA) to the mound. In his first outing, a 9-7 loss to the Los Angeles Angels, he received a no-decision, pitching six innings and allowing three earned runs, while walking zero batters and striking out four. In 60 games, including six starts in 2024, he went 3-4 with a 4.40 ERA, allowing 81 hits, 42 earned runs and 28 walks, while striking out 76 in 86 innings. He has faced the Pirates eight times, going 1-2.
Veteran third baseman Nolan Arenado is off to a fast start to the season. He has hits in all nine games, including three multi-hit performances. In a 12-5 win over the Angels on Wednesday, he was 2-for-3 with two RBI. For the season, he is hitting .343 with three doubles, one homer, six RBI and six runs scored. See which team to back at SportsLine.
Why the Pirates can cover
Pittsburgh will counter with right-hander Carmen Mlodzinski (0-1, 9.82 ERA). In his first outing this year, a 6-1 loss at Tampa Bay on March 31, he pitched 3.2 innings, allowing four earned runs and two walks, while striking out four. In 40 games last season, including four starts, he went 5-5 with a 3.38 ERA with 19 walks and 46 strikeouts. In seven career games against St. Louis, he is 1-0 with a 1.13 ERA with two walks and 12 strikeouts.
Second baseman Isiah Kiner-Falefa helps power the Pittsburgh offense. In 10 games this season, he is hitting .323 with one double and two RBI. He has walked five times and stolen four bases. In his eight-year MLB career, he is hitting .263 with 110 doubles, 14 triples, 34 homers and 248 RBI. He has hit the Cardinals well. In 11 career games against them, he is batting .394 with five doubles and one RBI. See which team to back at SportsLine.
How to make Cardinals vs. Pirates picks
SportsLine’s model is leaning Over on the total, projecting 10.1 combined runs, and it says one side of the money line has all the value. You can head to SportsLine to see the model’s MLB picks.
So who wins Cardinals vs. Pirates, and which side has all the value? Visit SportsLine now to see which side you need to jump on, all from the model that has crushed its MLB picks, and find out.
Where to bet on MLB games
Here are some of the sportsbooks to bet on MLB games today, along with the various MLB sportsbook promos they currently offer.
This news was originally published on this post .
About the author
Buffalo Bills Day 3 mock draft: Trading up for a falling value, targeting special teams
The first two days of the 2025 NFL Draft have concluded, and the Bills held true to their promise by using all three of their early picks on defense. The trio of cornerback Maxwell Hairston, defensive tackle T.J. Sanders and edge rusher Landon Jackson all have the potential to turn into starting players for the Bills over time.AdvertisementBut with the first two days done, it’s time to shift into the depth of the draft and the third day. Saturday will hold the final four rounds, with the Bills holding seven picks at Nos. 132, 169, 170, 173, 177, 206 and 240.And if there’s one thing the Bills have been able to do well over the years in the NFL draft, it’s finding some Day Three gems who turn into down-the-line starters. Since general manager Brandon Beane’s first Bills draft in […]
In Trey Amos, Commanders again get a player atop their board on Day 2 of NFL Draft
ASHBURN, Va. — Forget whether fans approve of the Washington Commanders’ second-round selection. Drafting former Ole Miss cornerback Trey Amos 61st overall had members of the organization’s research and development department roaring with delight.“I don’t know if you guys could hear,” general manager Adam Peters said to local media members moments later, “but our R&D department was probably the loudest.”AdvertisementThe approval wasn’t a display of Ole Miss fandom. Amos, a physical 6-foot-1 press cornerback with 13 credited pass deflections last season, was the data analyst’s top-rated player entering Day 2 of the NFL Draft. They weren’t the only ones in the building who were ecstatic about adding the former Louisiana and Alabama transfer who faced Commanders quarterback Jayden Daniels in college.Peters shared that the 2024 first-team All-SEC defender was in consideration with the Commanders’ first-round selection, 29th overall, before landing […]
49ers add beef — and ferocity — to middle of their defense on Day 2 of NFL Draft
SANTA CLARA, Calif. — Five of the last seven tailbacks the San Francisco 49ers faced in 2024 ran for more than 100 yards and the team gave up 24 rushing touchdowns on the season, tied for the second most in the NFL.Those dubious statistics seemed to be on the 49ers’ mind on Friday as they focused on bolstering the middle of their defense, beginning with a 332-pound defensive tackle early in the second round and finishing with a 181-pound nickel cornerback late in the third.AdvertisementKyle Shanahan admitted last month’s free-agency period, one in which the team lost eight 2024 starters — “more than we ever (lost) before,” he said — had him nervous about filling those holes in the draft. He said he was feeling a lot better about his roster by the end of the day Friday.“I told John […]
How the Bengals altered their process to — perhaps — finally fix the OL drafting problem
CINCINNATI — Bengals offensive coordinator Dan Pitcher doesn’t go on many pro day visits. He traveled to Ohio State and Georgia this year with new offensive line coach Scott Peters alongside him every step of the way.They arrived in Athens, Georgia, with a target on UGA guard Dylan Fairchild and his teammate, Tate Ratledge.AdvertisementWhen Peters started working with Fairchild, and both locked arms, something special happened.“That’s really where it felt like a connection,” Fairchild said.Fairchild, a country-strong, 315-pounder from rural Georgia, started wrestling when he was 6 years old. It defined his transition to football and his becoming a two-year starter at left guard for the Bulldogs. Then there’s Peters, in his first season with Cincinnati, with a background in jujutsu and no stranger to the weight room, himself looking to test Fairchild’s technical skill and power.“I could feel my […]
Why the Browns passed on Shedeur Sanders again on Day 2, drafted Dillon Gabriel
Ralph Vacchiano NFL Reporter <!--> --> For most of the first two nights of the NFL Draft, the biggest surprise was the fact that Colorado quarterback Shedeur Sanders was not selected.But then, late in the third round, the Cleveland Browns found a way to top that.When they made their selection with the 90th overall pick on Friday night — their fifth pick of the first two days — they didn’t just pass on Sanders again. They passed on him in favor of a quarterback almost nobody thought would go in the first three rounds. Cleveland took Oregon quarterback Dillon Gabriel, a 24-year-old who stands just 5-foot-11 and was a six-year starter at three different schools.Nobody, anywhere, thought he had a shot of getting drafted ahead of Sanders. By this point, Sanders was already having a miserable draft experience. But the […]
In drafting Mason Taylor, Jets transform his father from longtime foe into biggest fan
For years, Jason Taylor mocked the Jets and their fans. It was hard to blame him — he was a Miami Dolphin lifer, a rival. He tormented the Jets during the prime of a Hall of Fame career, and he relished it. In 2004, he called their fans “ignorant.” In 2007, he said they “suck.” In 2009, he called Giants fans “classy” — and Jets fans, not so much. He even joked that he’d rather retire than play for the Jets. But then he did become a Jet.AdvertisementIn 2010, he signed with the Jets, a franchise on the rise under Rex Ryan’s guidance. They’d moved to their new facility in Florham Park a couple years earlier, and Taylor’s locker was in the back corner. He hung out there a lot, happy to chat with anyone — media, teammates, staffers — […]
Related
Buffalo Bills Day 3 mock draft: Trading up for a falling value, targeting special teams
The first two days of the 2025 NFL Draft have concluded, and the Bills held true to their promise by using all three of their early picks on defense. The trio of cornerback Maxwell Hairston, defensive tackle T.J. Sanders and edge rusher Landon Jackson all have the potential to turn into starting players for the Bills over time.AdvertisementBut with the first two days done, it’s time to shift into the depth of the draft and the third day. Saturday will hold the final four rounds, with the Bills holding seven picks at Nos. 132, 169, 170, 173, 177, 206 and 240.And if there’s one thing the Bills have been able to do well over the years in the NFL draft, it’s finding some Day Three gems who turn into down-the-line starters. Since general manager Brandon Beane’s first Bills draft in […]
In Trey Amos, Commanders again get a player atop their board on Day 2 of NFL Draft
ASHBURN, Va. — Forget whether fans approve of the Washington Commanders’ second-round selection. Drafting former Ole Miss cornerback Trey Amos 61st overall had members of the organization’s research and development department roaring with delight.“I don’t know if you guys could hear,” general manager Adam Peters said to local media members moments later, “but our R&D department was probably the loudest.”AdvertisementThe approval wasn’t a display of Ole Miss fandom. Amos, a physical 6-foot-1 press cornerback with 13 credited pass deflections last season, was the data analyst’s top-rated player entering Day 2 of the NFL Draft. They weren’t the only ones in the building who were ecstatic about adding the former Louisiana and Alabama transfer who faced Commanders quarterback Jayden Daniels in college.Peters shared that the 2024 first-team All-SEC defender was in consideration with the Commanders’ first-round selection, 29th overall, before landing […]
49ers add beef — and ferocity — to middle of their defense on Day 2 of NFL Draft
SANTA CLARA, Calif. — Five of the last seven tailbacks the San Francisco 49ers faced in 2024 ran for more than 100 yards and the team gave up 24 rushing touchdowns on the season, tied for the second most in the NFL.Those dubious statistics seemed to be on the 49ers’ mind on Friday as they focused on bolstering the middle of their defense, beginning with a 332-pound defensive tackle early in the second round and finishing with a 181-pound nickel cornerback late in the third.AdvertisementKyle Shanahan admitted last month’s free-agency period, one in which the team lost eight 2024 starters — “more than we ever (lost) before,” he said — had him nervous about filling those holes in the draft. He said he was feeling a lot better about his roster by the end of the day Friday.“I told John […]
How the Bengals altered their process to — perhaps — finally fix the OL drafting problem
CINCINNATI — Bengals offensive coordinator Dan Pitcher doesn’t go on many pro day visits. He traveled to Ohio State and Georgia this year with new offensive line coach Scott Peters alongside him every step of the way.They arrived in Athens, Georgia, with a target on UGA guard Dylan Fairchild and his teammate, Tate Ratledge.AdvertisementWhen Peters started working with Fairchild, and both locked arms, something special happened.“That’s really where it felt like a connection,” Fairchild said.Fairchild, a country-strong, 315-pounder from rural Georgia, started wrestling when he was 6 years old. It defined his transition to football and his becoming a two-year starter at left guard for the Bulldogs. Then there’s Peters, in his first season with Cincinnati, with a background in jujutsu and no stranger to the weight room, himself looking to test Fairchild’s technical skill and power.“I could feel my […]
Why the Browns passed on Shedeur Sanders again on Day 2, drafted Dillon Gabriel
Ralph Vacchiano NFL Reporter <!--> --> For most of the first two nights of the NFL Draft, the biggest surprise was the fact that Colorado quarterback Shedeur Sanders was not selected.But then, late in the third round, the Cleveland Browns found a way to top that.When they made their selection with the 90th overall pick on Friday night — their fifth pick of the first two days — they didn’t just pass on Sanders again. They passed on him in favor of a quarterback almost nobody thought would go in the first three rounds. Cleveland took Oregon quarterback Dillon Gabriel, a 24-year-old who stands just 5-foot-11 and was a six-year starter at three different schools.Nobody, anywhere, thought he had a shot of getting drafted ahead of Sanders. By this point, Sanders was already having a miserable draft experience. But the […]
In drafting Mason Taylor, Jets transform his father from longtime foe into biggest fan
For years, Jason Taylor mocked the Jets and their fans. It was hard to blame him — he was a Miami Dolphin lifer, a rival. He tormented the Jets during the prime of a Hall of Fame career, and he relished it. In 2004, he called their fans “ignorant.” In 2007, he said they “suck.” In 2009, he called Giants fans “classy” — and Jets fans, not so much. He even joked that he’d rather retire than play for the Jets. But then he did become a Jet.AdvertisementIn 2010, he signed with the Jets, a franchise on the rise under Rex Ryan’s guidance. They’d moved to their new facility in Florham Park a couple years earlier, and Taylor’s locker was in the back corner. He hung out there a lot, happy to chat with anyone — media, teammates, staffers — […]
Be the first to leave a comment