2025 U.S. Open odds and picks: Scottie Scheffler, Rory McIlroy predictions by model that hit PGA Championship

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Bryson DeChambeau enters the 2025 U.S. Open at Oakmont Country Club as the defending national champion. In addition, he has put together an impressive resume in majors recently. He’s finished sixth or better in five of the last six majors and the 14-time worldwide winner has two major championships to his name. However, DeChambeau and the rest of the 2025 U.S. Open field will be tested by one of the toughest courses in the national title rotation when Oakmont hosts its 10th U.S. Open starting Thursday, June 12. DeChambeau was 15th at Oakmont as a 22-year-old and returns as one of the top 2025 U.S. Open contenders. He’s +900 in the 2025 U.S. Open odds, behind only Scottie Scheffler (+320) and Rory McIlroy (+550), who won the season’s first two major championships. Before locking in your 2025 U.S. Open picks or entering any PGA DFS tournaments on sites like DraftKings and FanDuel, be sure to see the golf predictions and projected leaderboard from the proven computer model at SportsLine.

SportsLine’s proprietary model, built by DFS pro Mike McClure, has been red-hot since the PGA Tour resumed in June 2020. In fact, the model is up nearly $9,000 on its best bets since the restart, nailing tournament after tournament.

This same model has also nailed a whopping 15 majors entering the weekend, including the 2025 Masters — its fourth Masters in a row — and the 2025 PGA Championship. Anyone who has followed its sports betting picks could have seen massive returns on betting apps and when taking advantage of the latest FanDuel promo codeDraftKings promo code and Fanatics Sportsbook promo code

Now that the 2025 U.S. Open field is locked in and fans are deciding where to bet the U.S. Open, SportsLine simulated the tournament 10,000 times, and the results were surprising. Head to SportsLine now to see the projected leaderboard.

2025 U.S. Open predictions for Scottie Scheffler, Rory McIlroy, Jon Rahm

One shocker the model is calling at the U.S. Open 2025: Jon Rahm, a two-time major winner, and one of this year’s favorites, stumbles and barely cracks the top 10 of the leaderboard. Rahm cut Scheffler’s lead to one stroke on the back nine at the PGA Championship, but a stunning late-round collapse led to a t-8th finish. Rahm went bogey-double bogey-double bogey on the final three holes, prompting concerns about his acclimation to three-round events.

Now Rahm will take on Oakmont, where he was low amateur after recording a t-23rd finish in 2016. The 2021 U.S. Open champion hasn’t finished better than t-7th in a major championship since leaving the PGA Tour in December 2023 and he missed the 2024 U.S. Open entirely because of a foot infection. He’s still undoubtedly one of the most talented players in the world, but his inconsistency off the tee of late is a major concern with five-inch thick rough at Oakmont that isn’t graduated.

The model has also locked in its projection for Scottie Scheffler, who is coming off a dominant win at the PGA Championship. Scheffler got a late start to his 2025 PGA Tour season after sustaining a hand injury over the winter break. He was rusty in the first quarter of the year, finishing outside of the top 10 in three of his first five events.

He has roared back since that point, however, with five straight top-10 finishes. More impressively, he won back-to-back May tournaments, the CJ Cup Byron Nelson and PGA Championship. Scheffler appeared to be on the cusp of a U.S. Open title with three top-10 finishes between 2021-23, but took a step back last year with a T41.

Meanwhile, the model has examined Rory McIlroy’s chances of winning his sixth major tournament. McIlroy has racked up 29 career victories on the PGA Tour, including three wins in 2025. However, he struggled at the PGA Championship, finishing T-47.

McIlroy has had tremendous success this season thanks to his effectiveness on the green. The 36-year-old ranks third in putting average (1.694), fourth in one-putt percentage (45.66%) and eighth in strokes gained: putting (0.627). He also ranks first in strokes gained: off the tee (0.776) and third in driving distance (319.3), but has struggled with accuracy. In fact, McIlroy ranks 172nd in driving accuracy (51.13%), which could be something to consider given the tough conditions expected to be in play at Oakmont. See the full U.S. Open projections from the model here.

How to make 2025 U.S. Open picks

The model is also targeting four golfers with odds longer than 20-1 who will make a strong run at the title. Anyone who backs these longshots could hit it big. You can only see the model’s picks here.

Who will win the 2025 U.S. Open, which longshots will stun the golfing world, and where will Scottie Scheffler and Rory McIlroy finish? Check out the latest 2025 U.S. Open odds below and then visit SportsLine to see the projected leaderboard, all from the model that’s nailed 15 golf majors, including the last four Masters and last two PGA Championships.

2025 U.S. Open odds, favorites 

Get full 2025 U.S. Open picks, best bets and predictions here

Scottie Scheffler +320
Rory McIlroy +550
Bryson DeChambeau +900
Jon Rahm +1200
Xander Schauffele +1700
Ludvig Aberg +1800
Collin Morikawa +2200
Viktor Hovland +2600
Justin Thomas +3300
Brooks Koepka +3300
Tommy Fleetwood +3300
Shane Lowry +3600
Sungjae Im +4100
Matt Fitzpatrick +4100
Hideki Matsuyama +4100
Adam Scott +4100
Patrick Cantlay +4200
Tyrrell Hatton +5000
Min Woo Lee +5000
Sam Burns +5000
Justin Rose +5000
Tony Finau +5000
Cam Smith +5000
Wyndham Clark +5000
Tom Kim +6000
Corey Conners +6000
Si Woo Kim +6500
Russell Henley +6500
Sepp Straka +6500
Jordan Spieth +6500
Jason Day +6500
Brian Harman +8000
Max Homa +8000
Dustin Johnson +8000
Byeong Hun An +8000
Will Zalatoris +8000
Cameron Young +8000
Sahith Theegala +8000
Daniel Berger +9000
Christiaan Bezuidenhout +10000
Sergio Garcia +10000
Nick Dunlap +10000
Dean Burmester +10000
Akshay Bhatia +10000
Robert MacIntyre +10000
Alex Noren +10000
Keegan Bradley +10000
Ryan Fox +12000
Billy Horschel +12000
Davis Thompson +12000
Aaron Rai +12000
Rickie Fowler +12000
Nicolai Hojgaard +12000
Adam Hadwin +12000
Harris English +12000
J.T. Poston +15000
Victor Perez +15000
Kurt Kitayama +15000
Mackenzie Hughes +15000
Austin Eckroat +15000
Tom Hoge +15000
Erik van Rooyen +15000
Taylor Pendrith +15000
Adrian Meronk +15000
Denny McCarthy +15000
Matthieu Pavon +15000  

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