For the first time in nine years, the U.S. Open returns to Oakmont Country Club. Bryson DeChambeau, last year’s U.S. Open winner, will try to become the first back-to-back winner of the event since Brooks Koepka accomplished the feat in 2017 and 2018. This will be the third time that Oakmont will play host to the event, and the U.S. Open 2025 begins on Thursday with Round 1. Scottie Scheffler enters as the +280 favorite (risk $100 to win $280) in the 2025 U.S. Open odds, followed by DeChambeau (+700), Rory McIlroy (+1100) and Jon Rahm (+1200). Koepka is a +5000 (50-1) long shot. Who should you consider when you place your 2025 U.S. Open betting picks? Before locking in your 2025 U.S. Open picks, be sure to see the golf predictions and projected leaderboard from the proven computer model at SportsLine.
SportsLine’s proprietary model, built by DFS pro Mike McClure, has been red-hot since the PGA Tour resumed in June 2020. In fact, the model is up nearly $9,000 on its best bets since the restart, nailing tournament after tournament.
This same model has also nailed a whopping 15 majors entering the weekend, including the 2025 Masters – its fourth Masters in a row – and the 2025 PGA Championship. Anyone who has followed its sports betting picks could have seen massive returns on betting sites and for anyone taking advantage of the latest FanDuel promo code, DraftKings promo code and Fanatics Sportsbook promo code.
Now that the 2025 U.S. Open field is taking shape, SportsLine simulated the tournament 10,000 times, and the results were surprising. Head to SportsLine now to see the projected leaderboard.
2025 U.S. Open predictions
One major surprise the model is calling for at the 2025 U.S. Open: Rory McIlroy, a past U.S. Open champion and the third-favorite at +1100, stumbles and falls all the way out of the top five. Since winning the 2025 Masters, which completed his career grand slam, he has struggled of late. He missed the cut at the Zurich Classic on April 23.
At the Truist Championship on May 7, he finished tied for seventh. He followed that up with a 47th-place at the PGA Championship. Last week at the RBC Canadian Open, he missed the cut after posting a 71 and 78 for a nine-over-par 149. Despite all of his past successes, the model sees better value elsewhere. See who else to fade here.
Another surprise: Justin Thomas, a 40-1 longshot, makes a strong run at the title. He has a much better chance to win it all than his odds imply, so he’s a target for anyone looking for a huge payday. Thomas has been playing well in 2025, securing one win and six top-10 finishes across 13 starts. He finished on top of the leaderboard at the RBC Heritage, his first victory since the 2022 PGA Championship.
Thomas has been able to secure those positive results thanks in large part to his consistent putting stroke. The two-time major champion enters Oakmont ranked first in putting average (1.658), third in putts per round (27.72) and sixth in one-putt percentage (45.00%). Breaking par at a tough course like Oakmont will be a challenge for many golfers, but Thomas’ game seems well-suited for success at the U.S. Open. See who else to pick here.
How to make 2025 U.S. Open picks
The model is also targeting four other golfers with odds of 25-1 or longer who will make a strong run at the title. Anyone who backs these longshots could hit it big. You can only see the model’s picks here.
Who will win the 2025 U.S. Open, and which longshots will stun the golfing world? Check out the 2025 U.S. Open odds below and then visit SportsLine to see the projected leaderboard, all from the model that’s nailed 15 golf majors, including the last four Masters and the first two majors in 2025.
2025 U.S. Open odds, favorites
Get full 2025 U.S. Open picks, best bets, and predictions here.
(odds subject to change)
Scottie Scheffler +280
Bryson DeChambeau +700
Rory McIlroy +1100
Jon Rahm +1200
Xander Schauffele +2200
Collin Morikawa +2500
Ludvig Åberg +3000
Joaquin Niemann +3300
Tommy Fleetwood +4000
Justin Thomas +4000
Shane Lowry +4000
Patrick Cantlay +4500
Tyrrell Hatton +5000
Brooks Koepka +5000
Sepp Straka +5000
Jordan Spieth+5500
Viktor Hovland +5500
Hideki Matsuyama +6500
Corey Conners +7000
Ben Griffin +7000
Russell Henley +7000
Sam Burns +8000
Justin Rose +10000
Patrick Reed +10000
Keegan Bradley +10000
Matt Fitzpatrick +10000
Harris English +10000
Maverick McNealy +11000
Daniel Berger +11000
Tony Finau +11000
Si Woo Kim +11000
Robert MacIntyre +11000
Taylor Pendrith +12000
Aaron Rai +12000
Sungjae Im +12000
Jason Day +12000
Ryan Fox +12000
Cameron Young +15000
Wyndham Clark +15000
Cameron Smith +15000
Akshay Bhatia +15000
Min Woo Lee +15000
J.J. Spaun +15000
Thorbjørn Olesen +17000
Denny McCarthy +17000
Brian Harman +17000
Nick Taylor +17000
Andrew Novak +17000
Adam Scott +17000
J.T. Poston +17000
Dustin Johnson +17000
Ryan Gerard +22000
Gary Woodland +22000
Lucas Glover +22000
Michael Kim +22000
Carlos Ortiz +22000
Davis Thompson +22000
Marc Leishman +22000
Tom Kim +22000
Bud Cauley +25000
Max Greyserman +25000
Byeong Hun An +25000
Thomas Detry +25000
Eric Cole +25000
Rasmus Neergaard-Petersen +27000
Johnny Keefer +30000
Stephan Jaeger +30000
Tom Hoge +30000
Sam Stevens +30000
Rasmus Højgaard +30000
Jordan Smith +30000
Jackson Koivun +30000
Phil Mickelson +30000
Mackenzie Hughes +30000
Matt Wallace +30000
Davis Riley +35000
Christiaan Bezuidenhout +35000
Jhonattan Vegas +35000
Erik van Rooyen +35000
Niklas Norgaard +35000
Doug Ghim +35000
Nico Echavarria +40000
Matt McCarty +40000
Matthieu Pavon +40000
Jacob Bridgeman +40000
Cam Davis +40000
Chris Kirk +40000
Richard Bland +40000
Emiliano Grillo +40000
Victor Perez +40000
Laurie Canter +50000
Chris Gotterup +50000
Mark Hubbard +50000
Takumi Kanaya +50000
Ben James +60000
Michael La Sasso +60000
Justin Lower +60000
Jinichiro Kozuma +75000
Joe Highsmith +75000
Sam Bairstow +75000
Matthew Jordan +75000
Edoardo Molinari +75000
Emilio Gonzalez +100000
Evan Beck +100000
Alistair Docherty +100000
Joakim Lagergren +100000
Alvaro Ortiz +100000
Ryan McCormick +100000
Tyler Weaver +100000
Riley Lewis +100000
Joey Herrera +100000
Frederic LaCroix +100000
Andrea Pavan +100000
Mason Howell +100000
Matt Vogt +100000
James Hahn +100000
Adam Schenk +100000
Jacques Kruyswijk +100000
Kevin Velo +100000
Trevor Cone+100000
James Nicholas +100000
Grant Haefner +100000
Brady Calkins +100000
Noah Kent +100000
Yuta Sugiura +100000
Lanto Griffin +100000
Justin Hicks +100000
Will Chandler +100000
Trevor Gutschewski +100000
Brian Campbell +100000
Scott Vincent +100000
Thriston Lawrence +100000
Chandler Blanchet +100000
George Kneiser +100000
Trent Phillips +100000
Zachery Pollo +100000
Frankie Harris +100000
Bryan Lee +100000
Jackson Buchanan +100000
Philip Barbaree +100000
Cameron Tankersley +100000
Justin Hastings +100000
Guido Migliozzi +100000
Nick Dunlap +100000
Preston Summerhays +100000
George Duangmanee +100000
Zac Blair +100000
Jose Luis Ballester Barrio +100000
Roberto Díaz +100000
Austen Truslow +100000
Harrison Ott +100000
Zach Bauchou +100000
Lance Simpson +100000
Maxwell Moldovan +100000
Chase Johnson +100000
Riki Kawamoto +100000
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