The Pittsburgh Pirates meet the Chicago Cubs in the second of a four-game weekend series in a National League Central matchup on Friday afternoon. Chicago earned a 3-2 win on Thursday night. The Pirates (28-42), who have won five of the past seven games and will start ace Paul Skenes, are 9-23 on the road this season. The Cubs (42-27), who have lost five of nine, are 21-11 on their home field in 2025.
First pitch from Wrigley Field in Chicago is set for 2:20 p.m. ET. The Cubs have won seven of the past 10 meetings with the Pirates. Chicago is a -114 favorite on the money line (risk $114 to win $100) in the latest Cubs vs. Pirates odds from DraftKings Sportsbook, while the total number of runs Vegas thinks will be scored, or the over/under, is 7. Before making any Pirates vs. Cubs picks, be sure to see the MLB predictions and betting advice from SportsLine’s proven computer model.
The SportsLine Projection Model simulates every MLB game 10,000 times. It enters Week 12 of the 2025 MLB season on a 27-23 run on top-rated MLB sides picks. It has excelled making home run prop picks, returning more than 35 units of profit over the past two months. Anybody following at sportsbooks and on betting apps could have seen strong returns.
Now, the model has set its sights on Pirates vs. Cubs and just locked in its picks and MLB predictions. You can head to SportsLine now to see the model’s picks. Here are several MLB odds and betting lines for Cubs vs. Pirates which you can get in on with a DraftKings promo code or a FanDuel promo code.
|
Cubs vs. Pirates money line |
Pittsburgh -105, Chicago -114 at DraftKings Sportsbook |
|
Cubs vs. Pirates over/under |
7 runs |
|
Cubs vs. Pirates run line |
Pittsburgh -1.5 (+163) |
|
Cubs vs. Pirates picks |
|
|
Cubs vs. Pirates streaming |
Fubo (Try for free) |
Why the Cubs can win
Chicago is expected to send right-hander Cade Horton (3-1, 4.11 ERA) to the mound. In six games, including five starts, he has pitched 30.2 innings, allowing 33 hits, 14 earned runs and seven walks with 25 strikeouts. He took the loss in a 4-0 defeat at Detroit on Sunday. In that game, he pitched five innings, allowing seven hits, four earned runs and two walks, while striking out six. He has allowed three or fewer earned runs in five games.
Helping power the offense is second baseman Nico Hoerner. In 65 games, he is batting .285 with 16 doubles, one triple and 29 RBI. In Wednesday’s 7-2 loss to the Philadelphia Phillies, he was 2-for-4 with a double and an RBI. He was 2-for-4 with a walk in an 8-4 victory over Philadelphia on Tuesday. He has feasted on Pirates pitching throughout his career, hitting .358 in 51 career games, including 12 doubles, two triples, four homers and 31 RBI. See which team to back at SportsLine.
Why the Pirates can win
Skenes (4-6, 1.88 ERA) is expected to start for Pittsburgh. He has allowed two or fewer runs in each of his last seven outings. In 14 starts this season, he has pitched 91 innings, allowing 56 hits, 19 earned runs and 20 walks with 92 strikeouts. He received a no-decision in his last appearance, a 2-1 win over the Philadelphia Phillies on Sunday. In that game, he pitched 7.2 innings, allowing two hits, one run – none earned – with one walk and seven strikeouts.
Among Pittsburgh’s top hitters is second baseman Adam Frazier. In 62 games, he is batting .259 with nine doubles, three homers and 18 RBI. In a 10-3 win over the Miami Marlins on Monday, he was 3-for-5 with an RBI. He was also 3-for-4 with a double in a 5-4 win over the Phillies on June 6. See which team to back at SportsLine.
How to make Cubs vs. Pirates picks
SportsLine’s model is leaning Over on the total, projecting 8.1 combined runs, and it says one side of the money line has all the value. You can head to SportsLine to see the model’s MLB picks.
So who wins Cubs vs. Pirates, and which side of the money line has all the value? Visit SportsLine now to see which side you need to jump on, all from the model that has crushed its MLB picks, and find out.
This news was originally published on this post .
About the author
Ex-UNC coach Mack Brown reflects on Bill Belichick’s $13M head start
Bill Belichick's unprecedented leap into college football at North Carolina has shifted the national spotlight to Chapel Hill, but for former Tar Heels head coach Mack Brown, the move is as bittersweet as it is historic. Watching Belichick walk into a program that has been drastically overhauled since his own departure, Brown is candid about the stark differences in the support and resources now available to his successor.Bill Belichick gets physical with his North Carolina playersBrown was let go after six seasons in his second stint at UNC, compiling a respectable 44-32 record. But in his view, he was coaching with one arm tied behind his back. In contrast, Belichick steps into a program that has undergone a major transformation - backed by a $13 million injection into football operations, plus sweeping academic and recruiting accommodations that were never extended […]
Lamar Jackson was able to avenge the injustice he experienced with Josh Allen the previous season; the controversy between the two quarterbacks continues
Last season there was a controversy that still sparks many debates among NFL experts and fans. On February 6, after a fantastic season with 40 total touchdowns, Josh Allen managed for the first time in his career to be named MVP at the NFL Honors ceremony. For many it was deserved, for others it was not.Josh Allen vs Joe Burrow: Highlights that fuel the debateThe situation was that Lamar Jackson had better numbers, superior to those of Josh Allen. However, in the MVP voting, Allen received 27 votes to the Baltimore Ravens quarterback's 23, who has already won league MVP twice. An anonymous voice said: "It's a shame that voter fatigue robbed Lamar of his third MVP... By every imaginable metric, he deserved it."It was very curious, because just weeks earlier, Lamar Jackson had been selected as the All-Pro starting […]
Bill Belichick and North Carolina exposed by TCU with Michael Jordan present
What began as a historic debut for Bill Belichick at North Carolina quickly spiraled into a nightmare, With the Tar Heel sideline packed by star alumni and cultural icons, including Michael Jordan and Mia Hamm, plus the coach's girlfriend Jordon Hudson cheering in UNC blue, expectations were sky high.Instead, UNC trailed 41-14 at the end of the third quarter, their offense stalling and defense overwhelmed. This turned the debut into a harsh reminder of just how much the jump from NFL to college sideline can be misjudged.Florida Gators player has the early catch of the year resembling Odell Beckham Jr.A debut overshadowed by a collapseBelichick entered Monday night carrying the weight of his soried NFL career, but the Tar Heels looked nothing like a team coached by the six time Super Bowl champion. By the beginning of the fourth quarter, […]
Galvão Bueno fica surpreso com nervosismo de Neymar no Santos e cita Ganso: “Eu nunca imaginei”
Neymar, em jogo do Brasileirão (Raul Baretta/ Santos FC)Galvão Bueno não esconde que ficou assustado ao abordar o temperamento de Neymar em Santos x Fluminense. Alvo de uma forte marcação, o craque teve uma tarde pouco inspirada, algo que trouxe mais nervosismo. Neste cenário, um momento específico de fúria na Vila Belmiro deixou o locutor surpreso, tendo em vista a rispidez envolvendo o contato com Paulo Henrique Ganso. PUBLICIDADE PUBLICIDADENa percepção de Galvão Bueno, a falta de brilho em campo está afetando o comportamento de Neymar. Indo às lágrimas após o atropelo sofrido pelo Santos contra o Vasco, o camisa 10 vem se esforçando para afastar o Peixe da zona de rebaixamento, mas a missão segue pendente, situação que vem elevando o nível de irritação. Além disso, a ausência na seleção brasileira também foi mencionada no discurso.“Eu acho que ele […]
Resultados da 22ª rodada do Brasileirão aumentam chances de rebaixamento de Atlético-MG, Corinthians e Santos
Logos de Corinthians, Santos e Atlético-MG (X oficial Corinthians / X oficial Santos / X oficial Atlético-MG)Ainda sem um técnico após a demissão de Cuca, o Atlético-MG terminou a 22ª rodada próximo da zona de rebaixamento após derrota para o Vitória pelo placar de 1 a 0. O tropeço fez o Galo cair para a 14ª posição, com dois pontos de distância para a equipe baiana, primeira dentro do Z4. O resultado fez o time mineiro aumentar suas chances de queda de 6.1% para 11.4, conforme dados do site Probabilidades No Futebol da UFMG. PUBLICIDADE PUBLICIDADEOs empates de Santos e Corinthians contra Fluminense e Palmeiras, respectivamente, também não foram suficientes para melhorar a situação dos clubes no Brasileirão. O Peixe hoje tem 34.4% de chances de ser rebaixado enquanto o Timão aparece com 12.8%.Porém os três alvinegros dependem apenas de […]
Jonas Urias, técnico do Cruzeiro, se emociona e desabafa: “Tudo vale a pena”
Jonas Urias, treinador do Cruzeiro, se emociona com classificação inédia no Brasileirão Feminino (Cris Mattos/Staff Images Woman/CBF)O Cruzeiro segue fazendo história no futebol feminino brasileiro. Então, após uma atuação histórica contra o Palmeiras no jogo de ida da semifinal do Brasileirão Feminino, tendo vencido por 3×1, as Cabulosas acabaram sendo derrotadas. PUBLICIDADE PUBLICIDADECom mais de 13 mil torcedores na Arena Independência, quem saiu na frente foi o Palmeiras. Porém, as Cabulosas buscaram o empate no segundo tempo e nos últimos minutos acabaram sofrendo um gol, perdendo a partida por 2×1. Entretanto, isso não abalou em nada o time mineiro que comemorou e muito a classificação inédita para à final do Brasileirão Feminino.Jonas Urias se emociona após a classificação históricaO treinador do Cruzeiro, Jonas Urias, ficou muito emocionado durante a comemoração da classificação para à final do Brasileirão Feminino. Então, destacou […]
Related
Ex-UNC coach Mack Brown reflects on Bill Belichick’s $13M head start
Bill Belichick's unprecedented leap into college football at North Carolina has shifted the national spotlight to Chapel Hill, but for former Tar Heels head coach Mack Brown, the move is as bittersweet as it is historic. Watching Belichick walk into a program that has been drastically overhauled since his own departure, Brown is candid about the stark differences in the support and resources now available to his successor.Bill Belichick gets physical with his North Carolina playersBrown was let go after six seasons in his second stint at UNC, compiling a respectable 44-32 record. But in his view, he was coaching with one arm tied behind his back. In contrast, Belichick steps into a program that has undergone a major transformation - backed by a $13 million injection into football operations, plus sweeping academic and recruiting accommodations that were never extended […]
Lamar Jackson was able to avenge the injustice he experienced with Josh Allen the previous season; the controversy between the two quarterbacks continues
Last season there was a controversy that still sparks many debates among NFL experts and fans. On February 6, after a fantastic season with 40 total touchdowns, Josh Allen managed for the first time in his career to be named MVP at the NFL Honors ceremony. For many it was deserved, for others it was not.Josh Allen vs Joe Burrow: Highlights that fuel the debateThe situation was that Lamar Jackson had better numbers, superior to those of Josh Allen. However, in the MVP voting, Allen received 27 votes to the Baltimore Ravens quarterback's 23, who has already won league MVP twice. An anonymous voice said: "It's a shame that voter fatigue robbed Lamar of his third MVP... By every imaginable metric, he deserved it."It was very curious, because just weeks earlier, Lamar Jackson had been selected as the All-Pro starting […]
Bill Belichick and North Carolina exposed by TCU with Michael Jordan present
What began as a historic debut for Bill Belichick at North Carolina quickly spiraled into a nightmare, With the Tar Heel sideline packed by star alumni and cultural icons, including Michael Jordan and Mia Hamm, plus the coach's girlfriend Jordon Hudson cheering in UNC blue, expectations were sky high.Instead, UNC trailed 41-14 at the end of the third quarter, their offense stalling and defense overwhelmed. This turned the debut into a harsh reminder of just how much the jump from NFL to college sideline can be misjudged.Florida Gators player has the early catch of the year resembling Odell Beckham Jr.A debut overshadowed by a collapseBelichick entered Monday night carrying the weight of his soried NFL career, but the Tar Heels looked nothing like a team coached by the six time Super Bowl champion. By the beginning of the fourth quarter, […]
Galvão Bueno fica surpreso com nervosismo de Neymar no Santos e cita Ganso: “Eu nunca imaginei”
Neymar, em jogo do Brasileirão (Raul Baretta/ Santos FC)Galvão Bueno não esconde que ficou assustado ao abordar o temperamento de Neymar em Santos x Fluminense. Alvo de uma forte marcação, o craque teve uma tarde pouco inspirada, algo que trouxe mais nervosismo. Neste cenário, um momento específico de fúria na Vila Belmiro deixou o locutor surpreso, tendo em vista a rispidez envolvendo o contato com Paulo Henrique Ganso. PUBLICIDADE PUBLICIDADENa percepção de Galvão Bueno, a falta de brilho em campo está afetando o comportamento de Neymar. Indo às lágrimas após o atropelo sofrido pelo Santos contra o Vasco, o camisa 10 vem se esforçando para afastar o Peixe da zona de rebaixamento, mas a missão segue pendente, situação que vem elevando o nível de irritação. Além disso, a ausência na seleção brasileira também foi mencionada no discurso.“Eu acho que ele […]
Resultados da 22ª rodada do Brasileirão aumentam chances de rebaixamento de Atlético-MG, Corinthians e Santos
Logos de Corinthians, Santos e Atlético-MG (X oficial Corinthians / X oficial Santos / X oficial Atlético-MG)Ainda sem um técnico após a demissão de Cuca, o Atlético-MG terminou a 22ª rodada próximo da zona de rebaixamento após derrota para o Vitória pelo placar de 1 a 0. O tropeço fez o Galo cair para a 14ª posição, com dois pontos de distância para a equipe baiana, primeira dentro do Z4. O resultado fez o time mineiro aumentar suas chances de queda de 6.1% para 11.4, conforme dados do site Probabilidades No Futebol da UFMG. PUBLICIDADE PUBLICIDADEOs empates de Santos e Corinthians contra Fluminense e Palmeiras, respectivamente, também não foram suficientes para melhorar a situação dos clubes no Brasileirão. O Peixe hoje tem 34.4% de chances de ser rebaixado enquanto o Timão aparece com 12.8%.Porém os três alvinegros dependem apenas de […]
Jonas Urias, técnico do Cruzeiro, se emociona e desabafa: “Tudo vale a pena”
Jonas Urias, treinador do Cruzeiro, se emociona com classificação inédia no Brasileirão Feminino (Cris Mattos/Staff Images Woman/CBF)O Cruzeiro segue fazendo história no futebol feminino brasileiro. Então, após uma atuação histórica contra o Palmeiras no jogo de ida da semifinal do Brasileirão Feminino, tendo vencido por 3×1, as Cabulosas acabaram sendo derrotadas. PUBLICIDADE PUBLICIDADECom mais de 13 mil torcedores na Arena Independência, quem saiu na frente foi o Palmeiras. Porém, as Cabulosas buscaram o empate no segundo tempo e nos últimos minutos acabaram sofrendo um gol, perdendo a partida por 2×1. Entretanto, isso não abalou em nada o time mineiro que comemorou e muito a classificação inédita para à final do Brasileirão Feminino.Jonas Urias se emociona após a classificação históricaO treinador do Cruzeiro, Jonas Urias, ficou muito emocionado durante a comemoração da classificação para à final do Brasileirão Feminino. Então, destacou […]
Be the first to leave a comment