2025 NFL Offensive Player Of The Year Odds: Saquon Barkley Early Favorite

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Philadelphia’s Saquon Barkley’s record-breaking season in 2024-25 earned him NFL Offensive Player of the Year honors.

He rushed for 2,005 yards last season and had 14 different games in which he hit the 100-yard rushing mark (including the postseason). And in the wake of his historic efforts, Barkley was rewarded with an extension that makes him the highest-paid running back in NFL history.

With all that in mind, it’s probably no surprise that he’s the early favorite at +650 to win OPOY again next season.

Let’s check out the early odds at DraftKings Sportsbook as of June 26.

2025-26 Offensive Player of the Year

Saquon Barkley, Eagles: +650 (bet $10 to win $75 total)
Ja’Marr Chase, Bengals: +950 (bet $10 to win $105 total)
Jahmyr Gibbs, Lions: +950 (bet $10 to win $105 total)
Bijan Robinson, Falcons: +1600 (bet $10 to win $170 total)
Nico Collins, Texans: +1700 (bet $10 to win $180 total)
Justin Jefferson, Vikings: +1700 (bet $10 to win $180 total)
Derrick Henry, Ravens: +1800 (bet $10 to win $190 total)
Puka Nacua, Rams: +2000 (bet $10 to win $210 total)
CeeDee Lamb, Cowboys: +2000 (bet $10 to win $210 total)
Christian McCaffrey, 49ers: +2200 (bet $10 to win $230 total)
Amon-Ra St. Brown, Lions: +3000 (bet $10 to win $310 total)
Tyreek Hill, Dolphins: +3000 (bet $10 to win $310 total)
Malik Nabers, Giants: +3000 (bet $10 to win $310 total)
Brian Thomas Jr., Jaguars: +3500 (bet $10 to win $360 total)
Lamar Jackson, Ravens: +4000 (bet $10 to win $410 total)

Tied for second on the board at +950 are Cincinnati’s Ja’Marr Chase and Detroit’s Jahmry Gibbs.

Though his Bengals failed to meet expectations last season by missing the postseason, Chase individually was phenomenal. 

He had 127 receptions, 1,708 receiving yards and 17 touchdowns — all good for the best in the NFL. While he was edged out by eventual winner in Barkley, the four-time Pro Bowler and 2021 Rookie of the Year was a finalist to win OPOY at the end of the season.

Meanwhile, Detroit’s Jahmyr Gibbs dominated last season. His 16 touchdowns in 2024 were the best in the NFL. And on the ground, he rushed for 1,412 yards, fifth-best in the league last season.

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Will Saquon Barkley drop off this season?

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Further down the board, at +4000, is Lamar Jackson.

The quarterback ended last year with a 27-25 playoff defeat at the hands of the Bills. However, the Ravens superstar had a dazzling season that led to him being honored as a finalist for OPOY and MVP.

Lamar’s 41 TDs were tied for fourth in the NFL and his 4,172 passing yards were sixth-best.

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