PFF Bets of the Week: NFL Week 5

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Week 5 is here, and PFF’s analysts have locked in their favorite bets of the week, powered by the PFF Player Prop Tool.

The tool delivers real-time projections, matchup data, hit rates and the best available odds — all in one place. It’s the same level of insight trusted by all 32 NFL teams, now at your fingertips.

Here are our analysts’ favorite bets for Week 5. These picks have gone 10-13-1 to start the year.

Trevor Sikkema (2-2)

RB Kenneth Walker III, Seattle Seahawks: Over 1.5 receptions (-135 BetMGM)

Walker has topped this number just once this season, catching only one pass in each of his last three games. However, he hit the mark in all 11 games he played last season. His 74.9 receiving grade ranks second on the team in 2025, and he now faces a Buccaneers defense that has struggled to contain running backs in the passing game.

Dalton Wasserman (3-1)

RB Cam Skattebo, New York Giants: Over 2.5 Receptions (+106 FanDuel)

Skattebo has taken over the lion’s share of snaps in the Giants’ backfield in recent weeks. With star wide receiver Malik Nabers out for the season and Tyrone Tracy likely sidelined again, Skattebo should see added involvement — particularly against a Saints defense that has allowed running backs to catch 94.4% of their targets, the third-highest rate in the NFL. Brian Daboll will need to get creative in the passing game, and Skattebo offers a natural solution.

Ben Linsey (3-1)

RB James Cook, Buffalo Bills: Under 80.5 rush yards (-115 BetM GM)

Cook has topped 100 rushing yards in three straight games, but this week presents a tougher challenge against New England. The Patriots rank fourth in rushing yards allowed to running backs through four weeks, a continuation of the run-stuffing identity Mike Vrabel established in Tennessee, where his defenses routinely led the league in yards allowed per carry.

With Cook’s rushing line climbing higher each week, I’m leaning toward the under in this difficult matchup.

Mason Cameron (0-3-1)

QB Jake Browning, Cincinnati Bengals: Under 225.5 passing yards (-115 Bet MGM)

Browning continues to struggle behind inconsistent protection, finishing with fewer than 150 passing yards in each of his two starts this season. Pressure remains a major issue — his 25.8 passer rating when pressured ranks last among 38 qualifying quarterbacks, and he’s averaging just 3.9 yards per attempt in those situations.

While Detroit hasn’t generated pressure at the same rate as Browning’s previous opponents, Aidan Hutchinson is starting to heat up and draws a favorable matchup against tackle Amarius Mims. It’s shaping up to be another long afternoon for the Bengals quarterback.

Max Chadwick (2-2)

TE Jake Ferguson, Dallas Cowboys: Over 4.5 receptions (-188 FanDuel)

Ferguson has gone over this number in every game this season and is averaging nearly 10 receptions per game over his last three outings. His 39 targets lead all tight ends by seven, and his 34 receptions are 10 more than the next closest player at the position. He also draws a favorable matchup against a Jets defense that allows targets to tight ends at the second-highest rate in the league.

Gordon McGuinness (0-4)

TE Brock Bowers, Las Vegas Raiders: Under 5.5 receptions (-148 Caesars)

Bowers has yet to clear this number through four games this season, and no tight end has recorded more than five receptions in a game against the Colts. While Bowers has been quarterback Geno Smith’s top target when under pressure, that’s mitigated by Smith’s struggles in those situations—his 35.5 PFF passing grade under pressure ranks 29th out of 33 qualifying quarterbacks.

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