Upset alert in Week 6? Why these five NFL favorites could fall, including Trevor Lawrence and the Jaguars

SPORTIVO
Article arrow_drop_down

Pandemonium is the best way to describe Week 5 in the NFL. The slate featured six double-digit comeback wins, which was tied for the most in a single week in league history. On top of that, several underdogs pulled off outright victories, including the Denver Broncos and New England Patriots, who knocked off the NFL’s two remaining undefeated teams in the Philadelphia Eagles and Buffalo Bills. It just goes to show you that just when you think you have the league figured out, it’ll zag in a hurry.

And the madness isn’t expected to slow down anytime soon, which includes a loaded Week 6 slate. Of course, upsets are commonplace in a given week, but identifying them proves to be the biggest challenge. Below, we’re going to take a look at five favorites and identify why they could be on upset alert in Week 6.

NFL odds courtesy of FanDuel Sportsbook. Bet NFL at FanDuel and get $300 in bonus bets with a winning $5 wager. You can get started here:

  • When: 1 p.m. ET | Where: EverBank Stadium (Jacksonville)
  • TV: Fox | Stream: (Fubo, try for free)
  • Seahawks ML odds: +100

Jacksonville is 4-1 and fresh off a prime-time win over the Kansas City Chiefs. It made timely plays on defense and can run the ball effectively. However, there are still major questions at quarterback with Trevor Lawrence. He had a number of errant throws on Monday night and ranks 24th among 33 qualified quarterbacks in EPA per dropback this season. Now, he faces a Seattle secondary that is allowing an 88.3 passer rating to opposing quarterbacks (11th best) this season.

The Seahawks are also surrendering just 3.3 yards per carry (No. 2 in the NFL) this season. If they eliminate that key strength of the Jaguars and put more on Lawrence’s arm, that could be a winning formula. Meanwhile, Seattle may have the quarterback edge with Sam Darnold, who is third in the NFL in EPA per dropback (0.32) and passer rating (114.8).

  • When: 1 p.m. ET | Where: Caesars Superdome (New Orleans)
  • TV: CBS | Stream: Paramount+
  • Saints ML odds: +168

New England is coming off a remarkable upset win at the Buffalo Bills, and they could be the next up-and-coming team. While that’s certainly on the table, this is still a young team that could be due for a letdown performance after such an emotional win. Remember, this is the same team that coughed the football up five times in a Week 3 loss to the Pittsburgh Steelers, so they may not be the model of consistency quite yet.

New Orleans is just 1-4 on the season, but the Saints have played hard in recent weeks. They gave the Bills a run for their money back in Week 4 and are coming off their first win of the season after taking down the Giants. At home, they have enough playmakers to hang around against New England and possibly clip them if the Patriots aren’t careful.

  • When: 4:05 p.m. ET | Where: Allegiant Stadium (Las Vegas)
  • TV: Fox | Stream: (Fubo, try for free)
  • Titans ML odds: +194

Las Vegas has fallen on its face with the Geno Smith experiment, as the veteran quarterback has been dreadful over the first five weeks. Smith already has three multi-interception games, including a two-pick showing in a blowout loss to the Colts last week. If Smith’s turnover woes continue, the Raiders will give any team that they face a puncher’s chance to pull off a win.

While Tennessee is also considered one of the AFC’s bottom dwellers, Cam Ward did flash his potential in the Titans’ improbable come-from-behind victory against the Arizona Cardinals in Week 5. Is it the spark that gets Tennessee rolling?

Detroit Lions at Kansas City Chiefs (-2.5)

  • When: 8:20 p.m. ET | Where: Arrowhead Stadium (Kansas City)
  • TV: NBC | Stream: (Fubo, try for free)
  • Lions ML odds: +118

Kansas City is in a bad way and letting fringe playoff teams take it down, as shown by its Monday night loss to the Jaguars. The Chiefs’ lone two wins this season came against the Giants and a banged-up Baltimore Ravens team that was missing Lamar Jackson for a chunk of the second half.

In Week 6, Kansas City hosts a Lions team that has been prolific on offense, averaging an NFL-best 34.8 points per game. This season, the Chiefs are giving up 4.8 yards per carry on the ground, which is tied for the NFL’s fifth-highest mark. That seems like a monumental mismatch against a Detroit backfield led by Jahmyr Gibbs and David Montgomery. And if the Lions run the ball effectively, that will further limit Patrick Mahomes‘ time of possession and reduce his chances of lifting a question cast around him.

  • When: 4:25 p.m. ET | Where: Raymond James Stadium (Tampa)
  • TV: CBS | Stream: Paramount+
  • 49ers ML odds: +130

It remains to be seen who’ll be available to the 49ers in Week 6, including the likes of Brock Purdy and George Kittle. That said, the Niners have shown us over the course of the season that they are capable of competing with a depleted roster, and Mac Jones has been more than serviceable under center. This season, Jones is 3-0 as a starter with a 67% completion rate while throwing for 301.7 passing yards per game and six touchdowns to just one interception.

So, even if it is Jones under center, San Francisco should be able to hang around, especially against a Bucs team that is routinely in one-score games. Tampa Bay is the first team in NFL history with four wins by three points or fewer in the first five games. What if that luck doesn’t fall the Bucs’ way in Week 6 with Kyle Shanahan coaching on the other sideline?

This news was originally published on this post .

About the author

About the author call_made

SPORTIVO

More posts

trending_flat
ATP roundup: Denis Shapovalov tops Leo Borg, son of Swedish legend, in Stockholm

Aug 30, 2025; Flushing, NY, USA; Denis Shapovalov (CAN) hits to Jannik Sinner (ITA) (not pictured) on day seven of the 2025 U.S. Open tennis tournament at the USTA Billie Jean King National Tennis Center. Mandatory Credit: Robert Deutsch-Imagn Images Canadian Denis Shapovalov overcame Leo Borg, the son of tennis legend Bjorn Borg, and the partisan crowd on Wednesday to advance to the quarterfinals of the BNP Paribas Nordic Open in Stockholm. Third-seeded Shapovalov, who won in Stockholm in 2019, defeated Swedish wild card Leo Borg 6-2, 5-7, 6-1. Borg, seeking his third career ATP Tour victory, saved 11 of 18 break points and converted 3 of 7 on his opportunities. Second-seeded Casper Ruud of Norway opened his tournament with a 7-6 (2), 6-4 victory over Marin Cilic to improve to 4-0 against the Croatian in this series. American Aleksander […]

trending_flat
G League, Next Gen players union announce CBA

The NBA G League Western Conference, left, and G League Championship trophies were on display at the Adventist Health Arena for a celebration event for the Kings’ win in the NBA G League Championship. The NBA's G League has come to an agreement with the Next Gen Basketball Players Union (NGBPU) on a collective bargaining agreement, the two sides announced Wednesday. The new CBA is scheduled to begin at tip off of the 2025-26 season and run for four years, through 2029. Notably, it represents a historic first, becoming the first multi-year CBA over the course of the G League's 25-year history. Though some specifics remain unsettled, the agreement provides an opt-out to both sides following the 2027-28 season, and provides for built in salary raises for players over the course of the deal, 4.7% (to $45,000) in Year 1, […]

trending_flat
Breece Hall Trade Destinations: New York Jets Trade Candidates

Dec 1, 2024; East Rutherford, New Jersey, USA; New York Jets running back Breece Hall (20) runs with the ball during the first quarter against the Seattle Seahawks at MetLife Stadium. Mandatory Credit: Mark Smith-Imagn Images The New York Jets have reached a point in the season where losing games might be more beneficial to them. There isn’t one reason why the Jets have been so bad this year. The whole team could really use a fresh coat of paint. Since the team is re-entering its never-ending rebuild, Breece Hall’s name has begun to pop up far more often in trade rumors. Hall is currently on the final year of his rookie contract, and with how this season has gone for New York, I’d be shocked to see him back on the Jets next year. Fortunately for Hall, he’s probably […]

Steelers vs. Bengals Thursday Night Football Week 7 Betting Predictions

The Cincinnati Bengals will host the Pittsburgh Steelers in a divisional matchup on Thursday. The Steelers are leading the AFC North with a 4-1 record through five games. The Bengals are shockingly sitting in second, posting a 2-4 record thus far. Pittsburgh’s been one of the biggest surprises in the NFL this season. They currently rank ninth in the league in points (.436) per play. They also feature an elite defense, ranking fifth in points allowed (.311) per play. The Steelers have a +2.4 point average scoring margin this season. Cincinnati is dealing with key injuries, and they’ve struggled to find any success in 2025. They rank 25th in points (.313) per play, and that total has unsurprisingly dipped since the injury to Joe Burrow. They aren’t better defensively, ranking 27th in points allowed (.458) per play. Overall, the Bengals […]

MLS Used AI To Write Match Recaps and It Went as Badly as You’d Expect

Never underestimate Major League Soccer’s ability to use technology stupidly.It took two full years partnering with Apple TV to realize it should harness the relationship to provide viewers with more matches to watch, not fewer. And while MLS was an early adopter of VAR, it has still dragged its feet on using virtual offside lines, semi-automated offsides systems or goal-line technology. Then came this weekend, as the league website began publishing match recaps written by Artificial Intelligence without any editorial oversight. It went about as poorly as you'd expect. Full disclosure: I worked as a freelance contributor for the site, mlssoccer.com, for the better part of a decade until 2022. There was predictable (and justified) outrage among the league’s underserved fans and undercompensated human journalists. In particular, longtime FC Cincinnati beat writer Laurel Pfahler correctly pointed out how far short […]

NBA Free Agency Watch: Where the Last Remaining Players Could Sign Before Opening Night

With the NBA season tipping off in just one week, we still have multiple free agents looking to find homes.Russell Westbrook finally found his home in Sacramento with the Kings. That’s certainly an interesting pairing, and one I don’t see working out. There are still plenty of available options to fill out the final open roster spots in the league. From veterans looking to squeeze out one more year, to young players looking to get a second chance, or even players dealing with interesting legal situations… looking at you, Malik Beasley. Let’s find some landing spots for a few remaining free agents. Kai Jones — Age 25: 5.0 PTS, 3.1 REB, 0.6 AST Jones is a very interesting player. He’s had his share of off-court battles, but he seems to be in the right headspace to prove he is a […]

Related

trending_flat
ATP roundup: Denis Shapovalov tops Leo Borg, son of Swedish legend, in Stockholm

Aug 30, 2025; Flushing, NY, USA; Denis Shapovalov (CAN) hits to Jannik Sinner (ITA) (not pictured) on day seven of the 2025 U.S. Open tennis tournament at the USTA Billie Jean King National Tennis Center. Mandatory Credit: Robert Deutsch-Imagn Images Canadian Denis Shapovalov overcame Leo Borg, the son of tennis legend Bjorn Borg, and the partisan crowd on Wednesday to advance to the quarterfinals of the BNP Paribas Nordic Open in Stockholm. Third-seeded Shapovalov, who won in Stockholm in 2019, defeated Swedish wild card Leo Borg 6-2, 5-7, 6-1. Borg, seeking his third career ATP Tour victory, saved 11 of 18 break points and converted 3 of 7 on his opportunities. Second-seeded Casper Ruud of Norway opened his tournament with a 7-6 (2), 6-4 victory over Marin Cilic to improve to 4-0 against the Croatian in this series. American Aleksander […]

trending_flat
G League, Next Gen players union announce CBA

The NBA G League Western Conference, left, and G League Championship trophies were on display at the Adventist Health Arena for a celebration event for the Kings’ win in the NBA G League Championship. The NBA's G League has come to an agreement with the Next Gen Basketball Players Union (NGBPU) on a collective bargaining agreement, the two sides announced Wednesday. The new CBA is scheduled to begin at tip off of the 2025-26 season and run for four years, through 2029. Notably, it represents a historic first, becoming the first multi-year CBA over the course of the G League's 25-year history. Though some specifics remain unsettled, the agreement provides an opt-out to both sides following the 2027-28 season, and provides for built in salary raises for players over the course of the deal, 4.7% (to $45,000) in Year 1, […]

trending_flat
Breece Hall Trade Destinations: New York Jets Trade Candidates

Dec 1, 2024; East Rutherford, New Jersey, USA; New York Jets running back Breece Hall (20) runs with the ball during the first quarter against the Seattle Seahawks at MetLife Stadium. Mandatory Credit: Mark Smith-Imagn Images The New York Jets have reached a point in the season where losing games might be more beneficial to them. There isn’t one reason why the Jets have been so bad this year. The whole team could really use a fresh coat of paint. Since the team is re-entering its never-ending rebuild, Breece Hall’s name has begun to pop up far more often in trade rumors. Hall is currently on the final year of his rookie contract, and with how this season has gone for New York, I’d be shocked to see him back on the Jets next year. Fortunately for Hall, he’s probably […]

Steelers vs. Bengals Thursday Night Football Week 7 Betting Predictions

The Cincinnati Bengals will host the Pittsburgh Steelers in a divisional matchup on Thursday. The Steelers are leading the AFC North with a 4-1 record through five games. The Bengals are shockingly sitting in second, posting a 2-4 record thus far. Pittsburgh’s been one of the biggest surprises in the NFL this season. They currently rank ninth in the league in points (.436) per play. They also feature an elite defense, ranking fifth in points allowed (.311) per play. The Steelers have a +2.4 point average scoring margin this season. Cincinnati is dealing with key injuries, and they’ve struggled to find any success in 2025. They rank 25th in points (.313) per play, and that total has unsurprisingly dipped since the injury to Joe Burrow. They aren’t better defensively, ranking 27th in points allowed (.458) per play. Overall, the Bengals […]

MLS Used AI To Write Match Recaps and It Went as Badly as You’d Expect

Never underestimate Major League Soccer’s ability to use technology stupidly.It took two full years partnering with Apple TV to realize it should harness the relationship to provide viewers with more matches to watch, not fewer. And while MLS was an early adopter of VAR, it has still dragged its feet on using virtual offside lines, semi-automated offsides systems or goal-line technology. Then came this weekend, as the league website began publishing match recaps written by Artificial Intelligence without any editorial oversight. It went about as poorly as you'd expect. Full disclosure: I worked as a freelance contributor for the site, mlssoccer.com, for the better part of a decade until 2022. There was predictable (and justified) outrage among the league’s underserved fans and undercompensated human journalists. In particular, longtime FC Cincinnati beat writer Laurel Pfahler correctly pointed out how far short […]

NBA Free Agency Watch: Where the Last Remaining Players Could Sign Before Opening Night

With the NBA season tipping off in just one week, we still have multiple free agents looking to find homes.Russell Westbrook finally found his home in Sacramento with the Kings. That’s certainly an interesting pairing, and one I don’t see working out. There are still plenty of available options to fill out the final open roster spots in the league. From veterans looking to squeeze out one more year, to young players looking to get a second chance, or even players dealing with interesting legal situations… looking at you, Malik Beasley. Let’s find some landing spots for a few remaining free agents. Kai Jones — Age 25: 5.0 PTS, 3.1 REB, 0.6 AST Jones is a very interesting player. He’s had his share of off-court battles, but he seems to be in the right headspace to prove he is a […]

Be the first to leave a comment

Leave a comment

Your email address will not be published. Required fields are marked *

Sportivo bridges the gap between talent and opportunity.

About SPORTIVO

Sportivo Network is a dedicated social platform for sports enthusiasts, athletes, and scouts. Whether you’re an aspiring athlete looking for opportunities, a coach searching for talent, or simply a sports lover wanting to connect with like-minded people, Sportivo is your go-to network. With features like direct messaging, profile showcasing, and talent scouting, Sportivo bridges the gap between talent and opportunity. Here, you can share your achievements, interact with professionals, and open doors to the next level in your sports journey. Join Sportivo Network – because every great athlete deserves to be discovered!
Copyright © 2025 SPORTIVO News. and SPORTIVO Network. All rights reserved.

Login to enjoy full advantages

Please login or subscribe to continue.

Go Premium!

Enjoy the full advantage of the premium access.

Stop following

Unfollow Cancel

Cancel subscription

Are you sure you want to cancel your subscription? You will lose your Premium access and stored playlists.

Go back Confirm cancellation