

The 25th-ranked Florida State Seminoles look to snap a two-game losing streak when they battle the Pittsburgh Panthers in a key ACC matchup on Saturday. Pitt is coming off a 48-7 win over Boston College, while FSU dropped a 28-22 decision to Miami last week. The Panthers (3-2, 1-1 ACC), who are tied for sixth in the conference, are 0-1 on the road this year. The Seminoles (3-2, 0-2 ACC), who are 16th in the league, are 3-1 on their home field in 2025.
Kickoff from Doak Campbell Stadium in Tallahassee, Fla., is at noon ET. The Seminoles are 10-point favorites in the latest Pittsburgh vs. Florida State odds, while the over/under for total points scored is 57.5 via SportsLine consensus. Before making any Florida State vs. Pitt picks, check out the college football predictions from the SportsLine Projection Model.
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The model simulates every FBS game 10,000 times. Since its inception, it has generated a betting profit of well over $2,000 for $100 players on its top-rated college spread football picks, and is a profitable 38-25 combined on money-line and over/under college football picks since the beginning of 2024. Anybody following its college football betting picks at sportsbooks and on betting sites could have seen strong returns.
Now, the model has set its sights on Pittsburgh vs. Florida State. You can visit SportsLine now to see the picks. Here are the FBS college football odds and trends for FSU vs. Pitt:
Pittsburgh vs. Florida State spread |
Florida State -10 at DraftKings Sportsbook |
Pittsburgh vs. Florida State over/under |
57.5 points |
Pittsburgh vs. Florida State money line |
Florida State -383, Pitt +301 |
Pittsburgh vs. Florida State picks |
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Pittsburgh vs. Florida State streaming |
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Why Florida State can cover
Senior quarterback Tommy Castellanos has powered the Seminoles through the air and on the ground. In five games, he has completed 70 of 115 passes (60.9%) for 1,120 yards and six touchdowns with five interceptions. He has also rushed 57 times for 274 yards (4.8 average) and four touchdowns. In the loss to Miami, he completed 25 of 45 passes for 272 yards and two touchdowns with two interceptions.
Junior wide receiver Duce Robinson has been the Seminoles’ top target in the passing game. In five games, he has 23 receptions for 433 yards (18.8 average) and three touchdowns. In a 46-38 double-overtime loss to Virginia on Sept. 26, he caught nine passes for 147 yards (16.3 average) and one touchdown. He caught five passes for 173 yards (34.6 average) and two touchdowns in a 77-3 win over East Texas A&M on Sept. 6. See which team to back at SportsLine.
Why Pittsburgh can cover
Freshman Mason Heintschel has taken over at quarterback for the Panthers. In last week’s win over Boston College, he completed 30 of 41 passes (73.2%) for 323 yards and four touchdowns. He also carried 10 times for 28 yards, including a long of 13. For the season, he has completed 33 of 45 passes (73.3%) for 359 yards and four scores.
Senior wide receiver Raphael Williams Jr. is among Pitt’s top targets in the passing game. In five games, he has 18 receptions for 320 yards (17.8 average) and four touchdowns. In a 31-24 overtime loss to West Virginia on Sept. 13, he caught six passes for 119 yards (19.8 average) and one touchdown. In a 45-17 win over Central Michigan on Sept. 6, he caught five passes for 81 yards and two touchdowns. See which team to back at SportsLine.
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How to make Pittsburgh vs. Florida State picks
SportsLine’s model is going Under on the total, projecting 53 combined points. It also says one side of the spread hits in over 60% of simulations. You can only get the pick at SportsLine.
So who wins Pittsburgh vs. Florida State, and which side of the spread hits over 60% of the time? Visit SportsLine now to see which side of the Pittsburgh vs. Florida State spread to jump on, all from the advanced model that finished up over $2,000 on its FBS college football picks since its inception, and find out.
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