2025 Indianapolis 500 odds, picks, prop bets: Expert who hit 17 winners eyeing nearly 80-1 longshot

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Veteran driver Alex Palou may have three IndyCar Series championships, but he is still seeking to win his first Indianapolis 500. Palou has come close with four top-10 finishes at the storied race, including fifth last year, when Josef Newgarden won his second consecutive Indianapolis 500 at Indianapolis Motor Speedway. Palou gets another shot on Sunday when he looks to make it five wins in six races this season. He is coming off a win at the 2025 Sonsio Grand Prix on May 10 at the Indianapolis Motor Speedway Road Course. The 2025 Indianapolis 500 starts at 12:45 p.m. ET on Sunday.

Pato O’Ward is the +500 favorite, with Palou at +550, Scott Dixon at +650 and Robert Schwartzman at +800 in the latest 2025 Indianapolis 500 odds from DraftKings Sportsbook. Before making any 2025 Indianapolis 500 picks or IndyCar Series predictions, you need to see what auto racing insider Steven Taranto has to say.

Taranto, who moonlights as a sim racer and has 20 career wins in iRacing, is the lead NASCAR writer for CBSSports.com. He has an annual NASCAR medial credential and also publishes a popular weekly NASCAR predictions column, famously calling Ross Chastain and Daniel Suarez’s breakthrough wins in 2022.

Taranto was red-hot for SportsLine in 2024 as he nailed 17 winners, including 16-1 longshot William Byron at the Daytona 500 and 14-1 longshot Chase Elliott at Texas. He correctly picked the Straight Talk Wireless 400 winner in Larson on March 23. Anyone following his NASCAR picks at their favorite sportsbooks could have seen huge returns.

Now, Taranto has analyzed the starting lineup and odds for Sunday’s 2025 Indianapolis 500 at Indianapolis Motor Speedway. He’s sharing his best bets at SportsLine. New users can use them to take advantage of the latest DraftKings promo code, FanDuel promo code or BetMGM promo code.

2025 Indianapolis 500 expert picks

One of Taranto’s top 2025 Indy 500 picks: He is high on Newgarden. Although the Penske scandal directly affects his team, Newgarden is a talented driver that has the ability to overcome any adversity thrown his way. Newgarden, at +1000 at DraftKings Sportsbook, remains in the mix to win his third consecutive Indianapolis 500. Newgarden has two top-10 finishes this season, including taking third at the season-opening Firestone Grand Prix of St. Petersburg.

Newgarden is a two-time IndyCar Series champion, winning titles in 2017 and 2019. In his 13-year IndyCar Series career, Newgarden has run 215 races. He has registered 31 wins, 58 podiums and 18 poles. He won his first race at the 2012 Grand Prix of St. Petersburg. See which other drivers he’s backing at SportsLine.

Top prop pick for Indianapolis 500

One surprising Indianapolis 500 prop Taranto is backing: He likes Christian Lundgaard (+105) to finish ahead of David Malukas (-135). Lundgaard, 23, is currently third in the series rankings with 155 points. He has four top-10 finishes, including second at the Children’s of Alabama Indy Grand Prix on May 4. He was also third at the Grand Prix of Long Beach and at The Thermal Club Grand Prix.

In his four-year IndyCar career, he has one win, five podiums and two poles in 52 races. Malukas, meanwhile, has not finished better than 13th this season, and is coming off a 23rd-place finish at the Grand Prix Road Course earlier this month. The 23-year-old, who is looking for his first career win, has run 44 races in his three-year career. See all of Taranto’s picks at SportsLine

How to make 2025 Indianapolis 500 predictions

Taranto has also identified three other drivers in his 2025 Indianapolis 500 best bets. He’s also high on a huge IndyCar longshot who’s going off at around 80-1, potentially netting any backer a huge payday. You can only see who they are here.

So who wins the 2025 Indianapolis 500 at Indianapolis Motor Speedway, and which massive longshot could stun IndyCar? Visit SportsLine now to see the 2025 Indianapolis 500 at Indianapolis Motor Speedway picks and best bets from a NASCAR insider who nailed a colossal 17 NASCAR winners last year, and find out.

2025 Indianapolis 500 at Indianapolis Motor Speedway odds, lineup

See full Indianapolis 500 at Indianapolis Motor Speedway picks at SportsLine

Pato O’Ward +500
Alex Palou +550
Scott Dixon +650
Robert Schwartzman +800
Takuma Sato +900
Scott McLaughlin +900
Josef Newgarden +1000
Felix Rosenqvist +1200
Kyle Larson +1800
David Malukas +1800
Alexander Rossi +1800
Christian Lundgaard +2000
Marcus Ericsson +2000
Kyle Kirkwood +2500
Conor Daly +2500
Colton Herta +2500
Will Power +2500
Santino Ferrucci +2500
Helio Castroneves +3000
Ed Carpenter +6000
Graham Rahal +8000
Sting Ray Robb +8000
Ryan Hunter-Reay +8000
Louis Foster +8000
Kyffin Simpson +10000
Jack Harvey +10000
Devlin DeFrancesco +10000
Christian Rasmussen +10000
Callum Ilott +10000
Rinus Veekay +10000
Nolan Siegel +10000
Marcus Armstrong +10000
Marco Andretti +10000    

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